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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880b6769e2a14004a8d0c046afb35f00af2beb6c9e2c42cccdda1dc370547c7d' 
  AND token = 't4Pb5GzeeUKKI2ndw0IOqJFMcxcWOareiHqbrZV7qK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}