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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11d04f8e2ecf16409be903990953e2907dfb34541cdca9710f475e32f6fc7040' 
  AND token = 'BgK8wx3ChPMato4sdH3WmnT1T8PHm8oRmTo3q8xmXWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}