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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c251eb0d81b5cdf34daa965b37f009640716798615f200ec4b334b0571d52e33' 
  AND token = 'eawugFJYTYFwrg24tdumwtuc8oMGSR8W4OJY6OfIMfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}