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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545f2f1a8b947bfb374dbbbd32cd70da777931f6181184f00bb545db8165c8f9' 
  AND token = 'IAkmWP/gH0E3weel+XCyQHj3LN6+gF+Fvv7/1QMLcAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}