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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110e3b2466a51c2b52d31f011786394756bb5a8cb3ed42ab54534b2e336ee2ce' 
  AND token = 'LiYFGELyG13OnbZSo4/jYPqUsfDt3+TeioxXbG3cI7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}