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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de85e5b7213b6bda1573f461b0147527580a1fb43faed8ae5d06fd0efcdca655' 
  AND token = 'hfFnUg5/2/tte0ttuB2+Uy95QSkmZNPAnUY3gISFUI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}