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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5ee862de60ce78b686b6dcdc16f640c0cf9a4833b2bcc4892ccc5143a8069a' 
  AND token = 'Z9QAxdN6rP2jgYMIoL5eYnWqOuu+kjfxJs0KbN1Bsf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}