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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943c5687e4df5917ebf643287f30b4d9d086951b24632807ba00e1f597b0e4ce' 
  AND token = 'zrwXcMDRYNQ+4+Xf3qtVk4TeDklYR2GfffBbaWdVU4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}