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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e325c6d683c249f14b33c6dac7f1e49ec85ef1e83f0c2c20db4366d2bdbab8a6' 
  AND token = 'JTgmcpXaZ928CQfhAx1SUucKdoI+wKVf6+FPe4SDyuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}