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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105f461e4a333d2e4806451f1148bf1bffaaecb5afb8b6959a2431045437250b' 
  AND token = 'Roa2I7m/jMjs0SXq/hI8erMgZQeTA2YrwQNK9e/MsQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}