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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd08339b92c64d3d91d9a87bda3a1d6787d2870c59239872bb2b6b4078362bf6b' 
  AND token = 'xYDiY4lDX5UPZyFuEEPF7T5eqk9hg6aFzZR3TNEhjqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}