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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f29c9c42c5160a68e3b7fde22c5fa65c762b68fe88028eb64d91acbaf7b3d021' 
  AND token = 'qJ2N5GnhHOO6zqiRd8UmeidNva5PXzZ2NIISgN/WnEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}