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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05851a4e1d4fcfa3cd91f842a821e937e02b6646a5b472b895e986175a8f5f4e' 
  AND token = 'j6tT11xccGMZS6uG9q98Tc9VBQ34Ta0GKJaHIqnGqGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}