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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effdd27fd27649355ba452b95da8f396b8cad94ab521135709539c373937d40c' 
  AND token = 'gYbknL2sK5ffKBnp3X4ldspHD6IaBVWUkKQ1no2Z8K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}