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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51db779f3d75fe1950ccb3d353f1bfa2ee4436321ffb32022f34daf47fa2d803' 
  AND token = 'hs8GsKQypb3KTHaOad2yoYxN4fQMoUmkTp1lHVFRJOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}