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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a6f50a0aab75b945d4e542b1d5a7eee3917611a87f1d84ce35f207f35e3dea' 
  AND token = 'is1eTFMzmnoUQc0ldlYDGLNJ60SAnT8kZwNIcxy9WRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}