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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a04cc22cfb60fd520ef5363bbcdf4da8d5a99327225ee7a2e20df0e90c074dc0' 
  AND token = 'tbzOEhd2phbM4Sk+f72zcEgui4RqUD41UONiz0NctAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}