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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3650ee93bfa45abcd1b736f235d64f7dc0359362b30d8b88d6add3949d26b6b2' 
  AND token = 'vdC9tyxgE2oMAMlRpOdwJ1B8DvyDm96Kob+jAtROk2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}