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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dde16a7e9189c58daf7c0b149c80f0e90e5af470e2e22bd9c568d1a747186411' 
  AND token = 'M95mR3rL2eXfGwYy++FYtdhyFnHn+yDOFwcwHWbpWwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}