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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a15829930857a3077e4f75c37f2fdb538c457f1c8060f2e73725f1c4c9b2e6' 
  AND token = 'BvNToN54y411wZZTR580kMTQC+idiwnlGteBtfA6iLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}