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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e99966623588685bdada07ce620127be76391426a9f7e4c1fad6c71e47c6e668' 
  AND token = 'Qdh/uFm9uaaAYXELO6oKBdSG9TMo4NbPbuTy6w3cBnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}