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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161ac4b612329b1b47c66bee3068ca3d5d7023d083acf322359871740d80916f' 
  AND token = 'MWIh/EEsK8jQjR/fDlguxz9X3Q49Q8r16VLybW3JctE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}