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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e00e45bc103e580df62f3b0e8005c42890adfe1c105d4055a206901f4ad352ba' 
  AND token = '0xFkq6x6u0i2Gvt868KMF0Et5WunfQoLUO4PgH55u48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}