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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5effebaa34cb887ee87149011906e986c39046ea5a4eb8253d3e81d6c215c30' 
  AND token = 'jTiPKJZMz5Ha4OKD2ZPIYB6Foj5/Ranac8fGXyQgdLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}