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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac2087ff00e0a0c05accafa5b5265f1646b19138f471a3a3bcc78688260484c2' 
  AND token = '+Q7yWOs7SrEtE8dYOCXtfAD5BH6EoLwhmBoXr+U6Qp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}