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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e39a07acf1f40a066f017e2d4b3af14aefd765a3e6b0d240532ea764aad564d' 
  AND token = '2YWjwxGKsio18o6uVug9E4QibQmcmL1NCTPyn+w5dIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}