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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d33c1b044b92a69a4b6abd627d2f963a727681b70067373c2cf2f1c1f933475' 
  AND token = 'FoZfEORQyxPxmCMsW2OWjB3Xhk3ZPD4EX+8r5+A1QtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}