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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d118304c85247a3a3cea654e1d002d9c40d052b1e33a386bafcb0562d419e5' 
  AND token = 'w2a1EAxHDdcTChKDafrUOeG3x4kgvx4bulNzL50FpeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}