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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5cbffc909c613a79f6535a75230f13eec8ae63ca3a78a64fa82c153b5a03127' 
  AND token = 'HX7Rk/hP0YwJhEsxwMBnAnE5AFzRIRq5OVV64WJYNes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}