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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d044a74bae0017f97f29a1aa3745b9fe57b15064af0c4967aee1df5a1671443' 
  AND token = 'qY+zg51oz3NLlv1AnTL1Q0prZVXI3Pl7NYYq1LjZmVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}