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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7d0578da2f7bff7bd4455a5d9d5441e49197c151995e724b667c1366f748f5' 
  AND token = 'HVuZnmfHGUoLOE+lDp2MlFkRT206mpZWNuNJtMeQyiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}