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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9378d04b87156e4457d7f68458b76f48848c7eb5fef16e40e885fef01bb4bf1a' 
  AND token = '1A3oVTjRODyQ6RKw/9u8vOpHM3g2ocrJLZrzoiEcGqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}