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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7c65de6bd20e9b7187c6531d33aea9ba81bfb89b4201c126f9de17c78443a5c' 
  AND token = 'FnMPk/sMCfnWGWEDVlE12lpM8w2YV2POk1fxYEZXxuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}