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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b54593f1defc5daf36b4ca8944b72f49f80149575ed9e9237ebddf08fc6dab55' 
  AND token = 'nRkgp4hijb30DzvPbs+iSErantyEK5FXlsIVIhxcg98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}