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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de77fdfcf5abae6c7d61067a529a2cf479a1e7c929b8ff9182d91445819c28ad' 
  AND token = 'k/tvgoPpDM6bnk9TBDHCY5pwzQDuop4T98OImo4rCqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}