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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '211a0c46bdd91059942f7272311b4e9a4b2df41744b2d0c5a5915a2abf7e5c66' 
  AND token = '+9Vrq3dks58w6TnJdBygIv5tzvBpAJRDFJq9z1lYBmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}