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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53d5b184bbead0c6c8d4dfe2d74b52ceb12797a59fd2ddb404aa46ad082c7ac' 
  AND token = 'nJur/j5ljEQOoIXgp7IGG2Ex1M76PWZb09aaARI5Vs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}