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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7df76dd4a28a7187b91b301b39675c49b55c22840b50b5f40d27ee8223d04af' 
  AND token = 'I7QknNbaP6LcXTNb4gQXvq1iVGxERrlHFIzMjUn7dsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}