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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736e9e453bebda1ebb52b259e76bcdbb4f8c054df7a31615ba0660b97cb87b12' 
  AND token = '2FdVbeap5WPOJJTqHBW0J+PwiCKB9cvzNjU8uC8hkMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}