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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7e4ca55d880991f9d1c4d723f5486658f67a7b3bc45d72ea333aab52612b24' 
  AND token = 'Ld52jZaNM/iLS+nA+74sfze1hHIt5XQBqbsLjujMv7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}