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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e3ac32e65b81648d03bc5d8b159c880aebcfc6015d7f235d03dd3e5729dd0b' 
  AND token = 'C/5bU75fTgPVCNsr5yPKh8yI4wIjOqfaVGS5oVNtZ6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}