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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea0ef659909f9c8ee3a2a1edc8a1489aa76b038c80cc89e15de54f848eddac93' 
  AND token = 'vxbeIcND2Ygsuk+wcyZIAWgvcAeiCDnrSmGIwO1batE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}