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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a976e55ad2037f401234e9b9f06499a7f7301fdd05da46c5a7b2a0354f896518' 
  AND token = 'VR5/zJwVFNIUw5U0ZapgksRCsV/WS1UDewbBuSOtfuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}