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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7ac0d5777a65fec4da10f06be87ecb2eecbc246ae54944f3d70b6d548605723' 
  AND token = '2UaduBbc+p5kGbzB3aXAk5PNOVDZ0K/264s6RdSpvLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}