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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc79743dc9c93372db4c2bfc323e27408bb5e979675337ec7765ed5845f5d71b' 
  AND token = 'wFlAOC0X0YdGoMO/fnZ5i6oYLw0g7PblptT8Y8XcTJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}