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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa6ba39eeada1dd9a55f3460723021356bacd53a11b4db4f65615408e99e29ac' 
  AND token = 'jPhG+lLgeb9NUHT4tjqnKQzJI9b16vtQfZ/3FsPQasM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}