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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9c22d901695411ce38b51863dadde93bab3a777aa87f429e6a3475b5fe1ca90' 
  AND token = 'lp3yxx1Q3UOzaW9KRxtaVPo8xhmq0mEDZmb+2fJdLmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}