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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e8d3237c5345e7a5983e75f723a21aff509271142bbe9c31d65947330cfa7dc' 
  AND token = 'XHlQDCZeCHeCvhiCZ3cp8uKg42KJhiQTi3nW/0V6ljE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}