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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ace4eb646e75656a3c0480dc421ac29c622abec5e9844a4046af117a44cab6' 
  AND token = 'RXGEzT8F+eelyDaMV3K7TseVQgz5nzb+EDnbeVKtvN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}