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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e0e8114834b0da42ba885471aee74f6d501c8ae95344976f4c6836999781df6' 
  AND token = 'ykYKuewjqb6nl0IEmEYvaQ+tLuQSw3u49FfGiV6ZI5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}